Submucosal injection of platelet-rich plasma in endoscopic resection of large sessile lesions.

ABSTRACT:

Aim

To prospectively evaluate the efficacy of submucosal injection of platelet-rich plasma (PRP) on endoscopic resection of large sessile lesions.

Methods

Eleven patients were submitted to endoscopic mucosal resection (EMR) with prior injection of PRP, obtained at the time of endoscopy. Patients were followed during 1 mo. The incidence of adverse events (delayed bleeding or perforation) and the percentage of mucosal healing (MHR) after 4 wk were registered.

Results

EMR was performed in 11 lesions (46.4 mm ± 4 mm, range 40-70 mm). Delayed bleeding or perforation was not observed in any patient. Mean ulcerated area at baseline was 22.7 cm² ± 11.7 cm² whereas at week 4 were 2.9 cm² ± 1.5 cm². Patients treated with PRP showed a

SUBMITTER: Lorenzo-Zuniga V 

PROVIDER: S-EPMC6247099 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature