Rotating night shift work and adherence to unhealthy lifestyle in predicting risk of type 2 diabetes: results from two large US cohorts of female nurses.

ABSTRACT:

Objectives

To prospectively evaluate the joint association of duration of rotating night shift work and lifestyle factors with risk of type 2 diabetes risk, and to quantitatively decompose this joint association to rotating night shift work only, to lifestyle only, and to their interaction.

Design

Prospective cohort study.

Setting

Nurses' Health Study (1988-2012) and Nurses' Health Study II (1991-2013).

Participants

143 410 women without type 2 diabetes, cardiovascular disease, or cancer at baseline.

Exposures

Rotating night shift work was defined as at least three night shifts per month in addition to day and evening shifts in that month. Unhealthy lifestyles included current smoking, physical activity levels below 30 minutes per day at moderate to vigo

SUBMITTER: Shan Z 

PROVIDER: S-EPMC6247172 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature