Quasi-Resonance Signal Amplification by Reversible Exchange.

ABSTRACT: Here we present the feasibility of NMR signal amplification by reversible exchange (SABRE) using radio frequency irradiation at low magnetic field (0.05 T) in the regime where the chemical shifts of free and catalyst-bound species are similar. In SABRE, the ¹⁵N-containing substrate and parahydrogen perform simultaneous chemical exchange on an iridium hexacoordinate complex. A shaped spin-lock induced crossing (SLIC) radio frequency pulse sequence followed by a delay is applied at quasi-resonance (QUASR) conditions of ¹⁵N spins of a ¹⁵N-enriched substrate. As a result of this pulse sequence application, ¹⁵N z-magnetization is created from the spin order of parahydrogen-derived hyperpolarized hydrides. The repetition of the pulse sequence block con

SUBMITTER: Theis T 

PROVIDER: S-EPMC6247415 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature