Phase II Trial of Acai Juice Product in Biochemically Recurrent Prostate Cancer.

ABSTRACT:

Background

Plant derivatives have been studied as therapies for prostate cancer based on their purported anti-inflammatory and antioxidant properties and low toxicities. The acai berry is an example of a plant rich in phytochemicals, which may slow the growth of prostate cancer.

Methods

This was a phase II, Simon 2-stage clinical trial in patients with biochemically recurrent prostate cancer with a primary endpoint of prostate-specific antigen (PSA) response. Patients were asymptomatic, with a rising PSA of at least 0.2 ng/mL, and were treated with twice daily intake of Acai Juice Product until PSA progression, with a primary endpoint of PSA response.

Results

Twenty-one patients were enrolled in the first stage of the trial. One of those patients had a PSA response wi

SUBMITTER: Kessler ER 

PROVIDER: S-EPMC6247557 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature