Linking Entropy at Rest with the Underlying Structural Connectivity in the Healthy and Lesioned Brain.

ABSTRACT: The brain is a network that mediates information processing through a wide range of states. The extent of state diversity is a reflection of the entropy of the network. Here we measured the entropy of brain regions (nodes) in empirical and modeled functional networks reconstructed from resting state fMRI to address the connection of entropy at rest with the underlying structure measured through diffusion spectrum imaging. Using 18 empirical and 18 modeled stroke networks, we also investigated the effect that focal lesions have on node entropy and information diffusion. Overall, positive correlations between node entropy and structure were observed, especially between node entropy and node strength in both empirical and modeled data. Although lesions were restricted to one hemisphere in all

SUBMITTER: Saenger VM 

PROVIDER: S-EPMC6248473 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature