Cancer Risk in Older Persons Living With Human Immunodeficiency Virus Infection in the United States.

ABSTRACT: Background:Cancer risk is increased in persons living with human immunodeficiency virus (HIV) (PLWH). Improved survival has led to an aging of PLWH. We evaluated the cancer risk in older PLWH (age ≥50 years). Methods:We included data from the HIV/AIDS Cancer Match Study (1996-2012) and evaluated risks of Kaposi sarcoma (KS), non-Hodgkin lymphoma (NHL), Hodgkin lymphoma, and cervical, anal, lung, liver, oral cavity/pharyngeal, breast, prostate, and colon cancers in older PLWH with risk in the general population by calculating standardized incidence ratios (SIRs) and excess absolute risks (EARs). Cancer risk by time since HIV diagnosis was estimated using Poisson regression. Results:We identified 10371 cancers among 183542 older PLWH. Risk was significantly increased for KS (SIR, 103.34), NH

SUBMITTER: Mahale P 

PROVIDER: S-EPMC6248478 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature