HETEROGENEITY OF GAIT SPEED RESPONSE TO INTENTIONAL WEIGHT LOSS IN OLDER ADULTS

ABSTRACT: Abstract Randomized controlled trial results in obese older adults consistently associate intentional weight loss of 5–10% with clinically meaningful improvement in gait speed, on average. Consideration of individual differences in response, however, has been largely ignored. The purpose of this study is to describe the inter-individual variability in gait speed response to intentional weight loss in overweight and obese older adults. Participants from the Intensive Diet and Exercise for Arthritis trial (NCT00381290), randomized to a caloric restriction intervention targeting 10% weight loss over 18 months were included, with fast-paced 6-minute walk assessed at baseline and 6 months. Of 112 participants (BMI: 33.6 ± 3.7 kg/m2; age: 66.7 ± 5.9 years), 79 experienced at least 5% weight loss

SUBMITTER: Beavers D 

PROVIDER: S-EPMC6248507 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature