Cognitive Reserve and Brain Maintenance: Orthogonal Concepts in Theory and Practice.

ABSTRACT: Cognitive Reserve and Brain Maintenance have traditionally been understood as complementary concepts: Brain Maintenance captures the processes underlying the structural preservation of the brain with age, and might be assessed relative to age-matched peers. Cognitive Reserve, on the other hand, refers to how cognitive processing can be performed regardless of how well brain structure has been maintained. Thus, Brain Maintenance concerns the "hardware," whereas Cognitive Reserve concerns "software," that is, brain functioning explained by factors beyond mere brain structure. We used structural brain data from 368 community-dwelling adults, age 20-80, to derive measures of Brain Maintenance and Cognitive Reserve. We found that Brain Maintenance and Cognitive were uncorrelated such that value

SUBMITTER: Habeck C 

PROVIDER: S-EPMC6248534 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature