Association of Neighborhood Socioeconomic Status With Risk of Infection and Sepsis.

ABSTRACT:

Background

Prior studies suggest disparities in sepsis risk and outcomes based on place of residence. We sought to examine the association between neighborhood socioeconomic status (nSES) and hospitalization for infection and sepsis.

Methods

We conducted a prospective cohort study using data from 30239 participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study. nSES was defined using a score derived from census data and classified into quartiles. Infection and sepsis hospitalizations were identified over the period 2003-2012. We fit Cox proportional hazards models, reporting hazard ratios (HRs) with 95% confidence intervals (CIs) and examining mediation by participant characteristics.

Results

Over a median follow-up of 6.5 years, there

SUBMITTER: Donnelly JP 

PROVIDER: S-EPMC6248765 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature