Network Structure among Brain Systems in Adult ADHD is Uniquely Modified by Stimulant Administration.

ABSTRACT: Current research in connectomics highlights that self-organized functional networks or "communities" of cortical areas can be detected in the adult brain. This perspective may provide clues to mechanisms of treatment response in psychiatric conditions. Here we examine functional brain community topology based on resting-state fMRI in adult Attention-Deficit/Hyperactivity Disorder (ADHD; n = 22) and controls (n = 31). We sought to evaluate ADHD patterns in adulthood and their modification by short term stimulants administration. Participants with ADHD were scanned one or two weeks apart, once with medication and once without; comparison participants were scanned at one time-point. Functional connectivity was estimated from these scans and community detection applied to determine cortical ne

SUBMITTER: Cary RP 

PROVIDER: S-EPMC6248828 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature