Child Neurodevelopmental Outcomes by Prepregnancy Body Mass Index and Gestational Weight Gain.

ABSTRACT:

Objective

To study the association of prepregnancy body mass index (BMI) and gestational weight gain with child neurodevelopmental outcomes.

Methods

We performed a secondary analysis of data from two parallel, multicenter, randomized, double-blind, placebo-controlled thyroxine replacement trials in pregnant women with either hypothyroxinemia or subclinical hypothyroidism who delivered at term. Body mass index was categorized as normal (18.5-24.9), overweight (25.0-29.9), or obese (30 or greater). We also evaluated early (20 weeks of gestation or less), late (greater than 20 weeks of gestation), and total gestational weight gain and categorized gestational weight gain as inadequate, adequate, and excessive per 2009 Institute of Medicine guidelines. Neurodevelopmental outcomes

SUBMITTER: Kominiarek MA 

PROVIDER: S-EPMC6249049 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature