Subjective Cognitive Impairment and the Broad Autism Phenotype.

ABSTRACT:

Introduction

Roughly 4% to 23% of the population embody stress prone personality and other traits characterizing a subclinical "broad autism phenotype" (BAP). Subjective cognitive impairment (SCI) among healthy elderly is associated with psychological distress leading us to predict BAP would be associated with SCI.

Methods

The Autism Spectrum Quotient, a self-administered 50 item questionnaire, was completed by 419 consecutive members of the Arizona APOE Cohort who underwent neuropsychological testing every 2 years. SCI was assessed with self and informant versions of the Multidimensional Assessment of Neurodegenerative Symptoms (MANS) Questionnaire.

Results

A total of 45 individuals scored in the BAP range, designated BAP+, and the rest were BAP-. At entry, both Mult

SUBMITTER: Caselli RJ 

PROVIDER: S-EPMC6249104 | biostudies-literature | 2018 Oct-Dec

REPOSITORIES: biostudies-literature