Radiomics score: a potential prognostic imaging feature for postoperative survival of solitary HCC patients.

ABSTRACT:

Background

Radiomics is an emerging field in oncological research. In this study, we aimed at developing a radiomics score (rad-score) to estimate postoperative recurrence and survival in patients with solitary hepatocellular carcinoma (HCC).

Methods

A total of 319 solitary HCC patients (training cohort: n = 212; validation cohort: n = 107) were enrolled. Radiomics features were extracted from the artery phase of preoperatively acquired computed tomography (CT) in all patients. A rad-score was generated by using the least absolute shrinkage and selection operator (lasso) logistic model. Kaplan-Meier and Cox's hazard regression analyses were used to evaluate the prognostic significance of the rad-score. Final nomograms predicting recurrence and survival of solitary HCC patien

SUBMITTER: Zheng BH 

PROVIDER: S-EPMC6249916 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature