Impact of Insulin Degludec in Type 2 Diabetes: Real-World Data on Effectiveness and Safety.

ABSTRACT:

Introduction

Real-world evidence on effectiveness and safety of insulin degludec (IDeg) in patients with diabetes is a priority. The aim of the study was to evaluate patterns of use and the long-term effectiveness and safety of IDeg in routine clinical practice.

Methods

This was an observational longitudinal study. A retrospective chart review of all patients with type 2 diabetes treated with IDeg was performed and temporal trends in clinical outcomes were assessed. All data was stratified by treatment modality: the switch group consisted of patients already treated with another basal insulin before initiating IDeg; the add-on group consisted of basal insulin-naïve patients.

Results

Overall, 247 patients were analyzed (55 in the add-on group and 192 in the switch grou

SUBMITTER: Ponzani P 

PROVIDER: S-EPMC6250625 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature