Defining Coronary Flow Patterns: Comprehensive Automation of Transthoracic Doppler Coronary Blood Flow.

ABSTRACT: The coronary microcirculation (CM) plays a critical role in the regulation of blood flow and nutrient exchange to support the viability of the heart. In many disease states, the CM becomes structurally and functionally impaired, and transthoracic Doppler echocardiography can be used as a non-invasive surrogate to assess CM disease. Analysis of Doppler echocardiography is prone to user bias and can be laborious, especially if additional parameters are collected. We hypothesized that we could develop a MATLAB algorithm to automatically analyze clinically-relevant and non-traditional parameters from murine PW Doppler coronary flow patterns that would reduce intra- and inter-operator bias, and analysis time. Our results show a significant reduction in intra- and inter-observer variability as w

SUBMITTER: Sunyecz IL 

PROVIDER: S-EPMC6250694 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature