Modelling the impact of a national scale-up of interventions on hepatitis C virus transmission among people who inject drugs in Scotland.

ABSTRACT:

Background and aims

To reduce hepatitis C virus (HCV) transmission among people who inject drugs (PWID), Scottish Government-funded national strategies, launched in 2008, promoted scaling-up opioid substitution therapy (OST) and needle and syringe provision (NSP), with some increases in HCV treatment. We test whether observed decreases in HCV incidence post-2008 can be attributed to this intervention scale-up.

Design

A dynamic HCV transmission model among PWID incorporating intervention scale-up and observed decreases in behavioural risk, calibrated to Scottish HCV prevalence and incidence data for 2008/09.

Setting

Scotland, UK.

Participants

PWID.

Measurements

Model projections from 2008 to 2015 were compared with data to test whether they were consisten

SUBMITTER: Fraser H 

PROVIDER: S-EPMC6250951 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature