Recommendation-based dietary indexes and risk of colorectal cancer in the Nurses' Health Study and Health Professionals Follow-up Study.

ABSTRACT:

Background

Many dietary indexes exist for chronic disease prevention, but the optimal dietary pattern for colorectal cancer prevention is unknown.

Objective

We sought to determine associations between adherence to various dietary indexes and incident colorectal cancer in 2 prospective cohort studies.

Design

We followed 78,012 women in the Nurses' Health Study and 46,695 men in the Health Professionals Follow-up Study from 1986 and 1988, respectively, until 2012. We created dietary index scores for the Dietary Approaches to Stop Hypertension (DASH) diet, Alternative Mediterranean Diet (AMED), and Alternative Healthy Eating Index-2010 (AHEI-2010) and used Cox regression to estimate HRs and 95% CIs for risk of colorectal cancer (CRC) and by anatomic subsite. We also cond

SUBMITTER: Petimar J 

PROVIDER: S-EPMC6250984 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature