Gene expression in reproductive organs of tsetse females - initial data in an approach to reduce fecundity.

ABSTRACT:

Background

Tsetse flies are vectors of African trypanosomes, and their vectorial capacity results in a major public health emergency and vast economic losses in sub-Saharan Africa. Given the limited ability of trypanosome prevention and eradication, tsetse vectors remain major targets of control efforts. Larvae of all three instars are developed in mothers' uteri, nourished through milk, and 'larviposited' shortly before pupation. The past few years have witnessed the emergence of approaches based on knockdown of genes involved in milk production, resulting in a significant reduction of fecundity.

Results

In order to identify further genes applicable in the control of tsetse flies, we determined the expression of protein-coding genes in ovaries and uteri from both virgin and

SUBMITTER: Prochazka E 

PROVIDER: S-EPMC6251150 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature