Tobacco Consumption and Toxicant Exposure of Cigarette Smokers Using Electronic Cigarettes.

ABSTRACT:

Background

There is considerable debate about the benefits and risks of electronic cigarettes (ECs). To better understand the risk-benefit ratio of ECs, more information is needed about net nicotine consumption and toxicant exposure of cigarette smokers switching to ECs.

Methods

Forty cigarette smokers (≥1 year of smoking) interested in switching to ECs but not necessarily quitting smoking were enrolled in a 4-week observational study and provided an e-Go C non-variable battery and refillable atomizers and choice of eight flavors in 12 or 24 mg nicotine dosage. Measurement of urinary cotinine (metabolite of nicotine), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL; a pulmonary carcinogen), and eight volatile organic compounds (VOCs) that are toxic tobacco smoke constitu

SUBMITTER: Pulvers K 

PROVIDER: S-EPMC6251645 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature