Breathing Disturbances Without Hypoxia Are Associated With Objective Sleepiness in Sleep Apnea.

ABSTRACT:

Study objectives

To determine whether defining two subtypes of sleep-disordered breathing (SDB) events-with or without hypoxia-results in measures that are more strongly associated with hypertension and sleepiness.

Methods

A total of 1022 participants with 2112 nocturnal polysomnograms from the Wisconsin Sleep Cohort were analyzed with our automated algorithm, developed to detect breathing disturbances and desaturations. Breathing events were time-locked to desaturations, resulting in two indices-desaturating (hypoxia-breathing disturbance index [H-BDI]) and nondesaturating (nonhypoxia-breathing disturbance index [NH-BDI]) events-regardless of arousals. Measures of subjective (Epworth Sleepiness Scale) and objective (2981 multiple sleep latency tests from a subset of 865 par

SUBMITTER: Koch H 

PROVIDER: S-EPMC6251661 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature