Interaction between Herpes Virus Infections and IL10 and Risk of Bone Marrow Suppression.

ABSTRACT:

Background

Syndrome of transient bone marrow suppression may result from various extra-hematological diseases, such as immunological deregulations, and viral infectious diseases secondarily affecting the function of hematopoietic stem cells.

Objective

To evaluate the pathogenic role of herpes viruses and their contraction with IL10 cytokine gene polymorphism, which can impair hematopoiesis in patients with transient bone marrow suppression.

Methods

In a cross-sectional study 30 patients who admitted to Namazi Hospital, affiliated to Shiraz University of Medical Sciences, with transient bone marrow suppression were recruited. Diagnosis of the transient bone marrow suppression was made by expert hematologists. A control group consisting of 100 healthy unrelated i

SUBMITTER: Yaghobi R 

PROVIDER: S-EPMC6252181 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature