Neuroimaging investigations of dorsal stream processing and effects of stimulus synchrony in schizophrenia.

ABSTRACT: Impairments in auditory and visual processing are common in schizophrenia (SP). In the unisensory realm visual deficits are primarily noted for the dorsal visual stream. In addition, insensitivity to timing offsets between stimuli are widely reported for SP. The aim of the present study was to test at the physiological level differences in dorsal/ventral stream visual processing and timing sensitivity between SP and healthy controls (HC) using MEG and a simple auditory/visual task utilizing a variety of multisensory conditions. The paradigm included all combinations of synchronous/asynchronous and central/peripheral stimuli, yielding 4 task conditions. Both HC and SP groups showed activation in parietal areas (dorsal visual stream) during all multisensory conditions, with parietal areas sh

SUBMITTER: Sanfratello L 

PROVIDER: S-EPMC6252286 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature