Differences in Stress-Induced Modulation of the Auditory System Between Wistar and Lewis Rats.

ABSTRACT: Many aspects of stress-induced physiological and psychological effects have been characterized in people and animals. However, stress effects on the auditory system are less explored and their mechanisms are not well-understood, in spite of its relevance for a variety of diseases, including tinnitus. To expedite further research of stress-induced changes in the auditory system, here we compare the reactions to stress among Wistar and Lewis rats. The animals were stressed for 24 h, and subsequently we tested the functionality of the outer hair cells (OHCs) using distortion product otoacoustic emissions (DPOAEs) and auditory neurons using evoked auditory brainstem responses (ABR). Lastly, using Western blot, we analyzed the levels of plasticity-related proteins in the inferior colliculus, co

SUBMITTER: Szczepek AJ 

PROVIDER: S-EPMC6252325 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature