Daily remote ischaemic conditioning following acute myocardial infarction: a randomised controlled trial.

ABSTRACT:

Background

Remote ischaemic conditioning (rIC) is a cardioprotective tool which has shown promise in preclinical and clinical trials in the context of acute ischaemia. Repeated rIC post myocardial infarction may provide additional benefits which have not previously been tested clinically.

Methods

The trial assessed the role of daily rIC in enhancing left ventricular ejection fraction (LVEF) recovery in patients with impaired LVEF (<45%) after ST segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (P-PCI). Patients were recruited from four UK hospitals and randomised to receive either 4 weeks of daily rIC or sham conditioning using the autoRIC Device (CellAegis) starting on day 3 post P-PCI. The primary endpoint was the impr

SUBMITTER: Vanezis AP 

PROVIDER: S-EPMC6252375 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature