Statin intensity and postoperative mortality following open repair of intact abdominal aortic aneurysm.

ABSTRACT:

Background

There is a lack of evidence for the association between intensive statin therapy and outcomes following vascular surgery. The aim of this study was to evaluate the association between perioperative statin intensity and in-hospital mortality following open abdominal aortic aneurysm (AAA) repair.

Methods

Patients undergoing open AAA repair between 2009 and 2015 were identified from the Premier Healthcare Database. Statin use was classified into low, moderate and high intensity, based on American College of Cardiology/American Heart Association guidelines. Supratherapeutic intensity was defined as doses higher than the recommended guidelines. Multivariable logistic regression analyses were undertaken to assess the association between statin intensity and postoperativ

SUBMITTER: Alshaikh HN 

PROVIDER: S-EPMC6254010 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature