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Serum lipid level is not associated with symptomatic intracerebral hemorrhage after intravenous thrombolysis for acute ischemic stroke.


ABSTRACT:

Background

This study assessed whether serum lipid levels are associated with the risk of symptomatic intracerebral hemorrhage (sICH) and functional outcomes in patients with acute ischemic stroke after receiving intravenous thrombolysis.

Methods

We retrospectively analyzed consecutive ischemic stroke patients who were treated with intravenous tissue plasminogen activator between January 2007 and January 2017. Lipid levels on admission, including total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride levels, as well as potential predictors of sICH were tested using univariate and multivariate analyses.

Results

Of the 229 enrolled patients (100 women, aged 68 ± 13 years), 14 developed sICH and 103

SUBMITTER: Lin TC 

PROVIDER: S-EPMC6254245 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature