In silico analysis of transferable QepA variants and related chromosomal efflux pumps.

ABSTRACT:

Objective

The present study aimed to detect the presence of undescribed QepA variants in GenBank records.

Methods

The DNA and amino acid sequences of QepA1 were compared with what is present in GenBank. Only annealings with a >80% identity were considered. No synthetic or partial sequences were included in the analyses.

Results

The results showed the presence of 10 different QepA variants, 6 of them which were previously non-designated as specific allelic variants. In addition, high identity levels with chromosomal MSF efflux pumps belonging to microorganisms of the Pseudorhodoferax genus and other Comamonadaceae were detected.

Conclusions

The presence of undescribed QepA variants in GenBank is reported and the presence of related sequences among members of Bur

SUBMITTER: Ruiz J 

PROVIDER: S-EPMC6254477 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature