Serum alkaline phosphatase and the risk of coronary heart disease, stroke and all-cause mortality: Tehran Lipid and Glucose Study.

ABSTRACT:

Objectives

To investigate the association of alkaline phosphatase (ALP) levels with the risk of the composite end point of cardiovascular disease (CVD), and all-cause mortality as well as each of them separately.

Design

Prospective cohort study.

Setting

Within the framework of the Tehran Lipid and Glucose Study (TLGS) cohort, participants were followed from baseline examination (1999-2001) until March 2014.

Participants

A total of 2578 participants, aged ≥30 years free of prevalent CVD at baseline examination.

Primary outcome

The main outcome measures were composite end point of coronary heart disease (CHD), stroke, all-cause mortality and each per se.

Results

During a median follow-up of 11.3 years, 369, 68, 420, 170 and 495 participants experien

SUBMITTER: Kabootari M 

PROVIDER: S-EPMC6254490 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature