Ontology highlight
ABSTRACT:
SUBMITTER: Sigal DS
PROVIDER: S-EPMC6254675 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Oncotarget 20181109 88
CGP results from >60,000 cases were screened to identify NTRK fusion events from cases of neuroendocrine tumors. 2417 NET patients from diverse anatomic sites were identified. From this dataset, six cases harbored NTRK fusions which included intra- and inter-chromosomal translocations. A NTRK fusion frequency of approximately 0.3% was found across all subtypes of NETs. Three cases involved translocations of NTRK1 with unique fusion partners (GPATCH4, PIP5K1A, CCDC19). Co-occurring alterations oc ...[more]