Systematic review of indoor residual spray efficacy and effectiveness against Plasmodium falciparum in Africa.

ABSTRACT: Indoor residual spraying (IRS) is an important part of malaria control. There is a growing list of insecticide classes; pyrethroids remain the principal insecticide used in bednets but recently, novel non-pyrethroid IRS products, with contrasting impacts, have been introduced. There is an urgent need to better assess product efficacy to help decision makers choose effective and relevant tools for mosquito control. Here we use experimental hut trial data to characterise the entomological efficacy of widely-used, novel IRS insecticides. We quantify their impact against pyrethroid-resistant mosquitoes and use a Plasmodium falciparum transmission model to predict the public health impact of different IRS insecticides. We report that long-lasting IRS formulations substantially reduce malaria, t

SUBMITTER: Sherrard-Smith E 

PROVIDER: S-EPMC6255894 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature