A glucose/O₂ fuel cell-based self-powered biosensor for probing a drug delivery model with self-diagnosis and self-evaluation.

ABSTRACT: Extending the application of self-powered biosensors (SPB) into the drug delivery field is highly desirable. Herein, a robust glucose/O₂ fuel cell-based biosensor is successfully integrated with a targeted drug delivery system to create a self-sustained and highly compact drug delivery model with self-diagnosis and self-evaluation (DDM-SDSE). The glucose/O₂ fuel cell-based biosensor firstly performs its diagnostic function by detecting the biomarkers of cancer. The drug delivery system attached on the anode of the glucose/O₂ fuel cell can be released during the diagnostic operation to guarantee the occurrence of a therapy process. Accompanied by the therapy process, the glucose/O₂ fuel cell-based biosensor can also act as an evaluation component

SUBMITTER: Wang L 

PROVIDER: S-EPMC6256853 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature