Agreement between renal prescribing references and determination of prescribing appropriateness in hospitalized patients with chronic kidney disease.

ABSTRACT:

Background

Chronic kidney disease (CKD) is a risk factor for adverse drug events. The clinical significance of discordance between renal prescribing references is unknown.

Aim

We determined the prevalence of potentially inappropriate prescribing (PIP) in CKD, measured agreement between two prescribing references, and assessed potential for harm consequent to PIP.

Design

Single-centre observational study.

Methods

A random sample of hospitalized patients with CKD were grouped according to baseline CKD stage (3, 4, or 5). Prescriptions requiring caution in CKD were referenced against the Renal Drug Handbook (RDH) and British National Formulary (BNF) to identify PIP (non-compliance with recommendations). Inter-reference agreement was measured using percentage agree

SUBMITTER: O'Shaughnessy M 

PROVIDER: S-EPMC6256938 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature