Activity for Diabetic Polyneuropathy (ADAPT): Study Design and Protocol for a 2-Site Randomized Controlled Trial.

ABSTRACT:

Background

Half of all patients with diabetes develop diabetic peripheral neuropathy (DPN), a complication leading to reduced mobility and quality of life. Although there are no proven pharmacologic approaches to reduce DPN risk or slow its progression, evidence suggests that physical activity may improve symptoms and enhance peripheral nerve regeneration.

Objective

The aim of the study will be to determine the impact of an intense lifestyle intervention on neuropathy progression and quality of life in individuals with DPN.

Design

The study will be a randomized controlled trial.

Setting

The study will be conducted at 2 academic medical centers.

Participants

The participants will be 140 individuals with type 2 diabetes and mild to moderate DPN.

Interve

SUBMITTER: Kluding PM 

PROVIDER: S-EPMC6257067 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature