Current Status and Future Perspectives of Axillary Management in the Neoadjuvant Setting.

ABSTRACT: Axillary surgery has undergone considerable changes in recent years, especially in relation to patients who undergo neoadjuvant chemotherapy (NACT). Due to constantly decreasing rates of recurrence and death from breast cancer, modern surgical strategies aim at de-escalating the extent of local treatment and avoiding unnecessary procedures. This relates especially to lymph node surgery which is associated with considerable morbidity. In patients who initially present with clinically node-negative disease, sentinel lymph node biopsy (SLNB) is increasingly performed after NACT. The determination of the post-NACT nodal status does not only spare patients from additional surgery but also allows the assessment of pathologic complete response which is increasingly becoming an important tool for

SUBMITTER: Kuhn T 

PROVIDER: S-EPMC6257201 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature