New strains of hepatitis B virus genotype E circulating in Nigeria.

ABSTRACT:

Objective

Hepatitis B virus (HBV) is not uncommon among persons infected with human immunodeficiency virus (HIV). Severity of HBV infection and treatment outcome are associated with specific HBV genotypes. No study has reported the types of HBV genotypes circulating among HIV-infected subjects in Nigeria. This study was designed to determine the prevalence of HBV, as well as its genotypic distribution among HIV-infected subjects in Benin City, Nigeria.

Methods

Whole blood was collected from a total of 564 HIV-infected and 250 apparently healthy HIV-negative subjects. Serodiagnosis of HBV infection was done using an immunochromatographic kit. Detection of HBV-DNA and sequencing of amplicons were done using standard molecular techniques.

Results

HIV status was not signi

SUBMITTER: Oladeinde BH 

PROVIDER: S-EPMC6257873 | biostudies-literature | 2018 Nov-Dec

REPOSITORIES: biostudies-literature