Prediction of peripheral nerve stimulation thresholds of MRI gradient coils using coupled electromagnetic and neurodynamic simulations.

ABSTRACT:

Purpose

As gradient performance increases, peripheral nerve stimulation (PNS) is becoming a significant constraint for fast MRI. Despite its impact, PNS is not directly included in the coil design process. Instead, the PNS characteristics of a gradient are assessed on healthy subjects after prototype construction. We attempt to develop a tool to inform coil design by predicting the PNS thresholds and activation locations in the human body using electromagnetic field simulations coupled to a neurodynamic model. We validate the approach by comparing simulated and experimentally determined thresholds for 3 gradient coils.

Methods

We first compute the electric field induced by the switching fields within a detailed electromagnetic body model, which includes a detailed atlas of p

SUBMITTER: Davids M 

PROVIDER: S-EPMC6258337 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature