American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia.

ABSTRACT:

Background

Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction mediated by platelet-activating antibodies that target complexes of platelet factor 4 and heparin. Patients are at markedly increased risk of thromboembolism.

Objective

These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and other health care professionals in their decisions about diagnosis and management of HIT.

Methods

ASH formed a multidisciplinary guideline panel balanced to minimize potential bias from conflicts of interest. The McMaster University GRADE Centre supported the guideline development process, including updating or performing systematic evidence reviews. The panel prioritized clinical questions and outcome

SUBMITTER: Cuker A 

PROVIDER: S-EPMC6258919 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature