Safety and efficacy of frequency-domain optical coherence tomography in evaluating and treating intermediate coronary lesions.

ABSTRACT:

Aim

To establish whether frequency-domain optical coherence tomography (FD-OCT) is safe and effective in the evaluation and treatment of angiographically-intermediate coronary lesions (ICL).

Methods

Sixty-four patients with 2-dimensional quantitative coronary angiography (2D-QCA) demonstrating ICL were included. OCT imaging was performed. According to predetermined OCT criteria, patients were assigned to either of 2 groups: OCT-guided percutaneous coronary intervention (PCI) or OCT-guided optimal medical therapy (OMT). The primary efficacy endpoint was to demonstrate the superiority and higher accuracy of FD-OCT compared to 2D-QCA in evaluating stenosis severity in patients with ICL. The primary safety endpoint was the incidence of 30-d major adverse cardiac events (MACE). S

SUBMITTER: Khurwolah MR 

PROVIDER: S-EPMC6259025 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature