In vivo evaluation of the new PHIL low viscosity in a swine rete mirabile model.

ABSTRACT:

Introduction

Few liquid embolic materials are available for treatment of arteriovenous malformations. We describe the in vivo experience with the new PHIL low viscosity (LV) liquid embolic agent in a swine rete mirabile model.

Methods

Eight swine were treated. Two animals underwent embolization of a rete with PHIL LV and the contralateral rete with Squid 12 (euthanized the same day). Six animals underwent embolization of the right rete: two with balloon flow arrest (euthanized at 14 d) and four with a microcatheter alone (euthanized at 14 and 90 d). Performance characteristics of the embolic agents were evaluated. Microscopic and histological analysis of the harvested retia was performed. Macroscopic examinations and high contrast digital-based radiographs of the central ner

SUBMITTER: Samaniego EA 

PROVIDER: S-EPMC6259347 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature