Neural dynamics of selective attention deficits in HIV-associated neurocognitive disorder.

ABSTRACT:

Objective

To identify the neural markers of attention dysfunction in patients with HIV-associated neurocognitive disorder (HAND).

Methods

Sixty participants, including 40 HIV-infected adults (half with HAND) and 20 demographically matched controls performed a visual selective attention task while undergoing high-density magnetoencephalography. Neuronal activity related to selective attention processing was quantified and compared across the 3 groups, and correlated with neuropsychological measures of attention and executive function. Spontaneous neural activity was also extracted from these attention-related cortical areas and examined with respect to HAND status.

Results

HIV-infected participants with and without HAND exhibited behavioral selective attention deficits

SUBMITTER: Lew BJ 

PROVIDER: S-EPMC6260195 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature