Predictors of alcohol responsiveness in dystonia.

ABSTRACT:

Objective

To determine predictors of alcohol responsiveness in a large cohort of patients with dystonia.

Methods

A total of 2,159 participants with dystonia were prospectively enrolled in the cross-sectional Dystonia Coalition multicenter study. Patients with secondary, combined, or confirmed genetic dystonia (total n = 164) or unknown alcohol responsiveness (n = 737) were excluded. Patients answered a standardized questionnaire and were clinically examined using a standardized video protocol and the Burke-Fahn-Marsden Dystonia Rating Scale. Alcohol responsiveness was determined by patients' self-report.

Results

A total of 1,258 patients with isolated dystonia (mean age: 59.5 ± 12.2 years; 898 women) met the inclusion criteria; 369 patients (29.3%) reported improvemen

SUBMITTER: Junker J 

PROVIDER: S-EPMC6260199 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature