The slow growing embryo and premature progesterone elevation: compounding factors for embryo-endometrial asynchrony.

ABSTRACT:

Study question

Is there an association of progesterone (P₄) on the day of trigger with live birth in autologous ART transfer cycles on day 5 versus day 6?

Summary answer

P₄ had a greater negative effect on live birth in day 6 fresh transfers compared to day 5 fresh transfers.

What is known already

Premature P₄ elevation is associated with lower live birth rates in fresh autologous ART cycles, likely due to worsened endometrial-embryo asynchrony. Few studies have evaluated whether the effect of an elevated P₄ on the day of trigger is different on live birth rates with a day 5 compared to a day 6 embryo transfer.

Study design size, duration

This was a retrospective cohort study with autologous IVF cycles with fresh embr

SUBMITTER: Healy MW 

PROVIDER: S-EPMC6260420 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature