Spliceosomal introns in Trichomonas vaginalis revisited.

ABSTRACT:

Background

The human protozoan parasite Trichomonas vaginalis is an organism of interest for understanding eukaryotic evolution. Despite having an unusually large genome and a rich gene repertoire among protists, spliceosomal introns in T. vaginalis appear rare: only 62 putative introns have been annotated in this genome, and little or no experimental evidence exists to back up these predictions.

Results

This study revisited the 62 annotated introns of T. vaginalis derived from the genome sequencing plus previous publications. After experimental validation and a new genome-wide search, we confirmed the presence of introns in 32 genes and 18 others were concluded to be intronless. Sequence analyses classified the validated introns into two types, based on distinctive features

SUBMITTER: Wang SE 

PROVIDER: S-EPMC6260720 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature