Influence of ¹³C Isotopic Labeling Location on Dynamic Nuclear Polarization of Acetate.

ABSTRACT: Dynamic nuclear polarization (DNP) via the dissolution method has alleviated the insensitivity problem in liquid-state nuclear magnetic resonance (NMR) spectroscopy by amplifying the signals by several thousand-fold. This NMR signal amplification process emanates from the microwave-mediated transfer of high electron spin alignment to the nuclear spins at high magnetic field and cryogenic temperature. Since the interplay between the electrons and nuclei is crucial, the chemical composition of a DNP sample such as the type of free radical used, glassing solvents, or the nature of the target nuclei can significantly affect the NMR signal enhancement levels that can be attained with DNP. Herein, we have investigated the influence of ¹³C isotopic labeling location on the DNP of a mod

SUBMITTER: Niedbalski P 

PROVIDER: S-EPMC6260835 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature