10-year follow-up of congenital cytomegalovirus infection complicated with severe neurological findings in infancy: a case report.

ABSTRACT:

Background

Congenital cytomegalovirus (cCMV) infection leads to sensorineural hearing loss (SNHL) and neurodevelopmental delays. However, the long-term outcomes of cCMV infection with severe neurological manifestations in infancy remain unclear.

Case presentation

The patient was a one-month-old girl visited owing to abnormalities in neonatal hearing screening. Central nervous system involvement including intracranial calcification and extensive white matter abnormalities was identified. Right SNHL (50 dB) was detected by auditory brain response (ABR) testing. The cause of her hearing loss was determined to be cCMV infection by polymerase chain reaction (PCR) using a dried blood spot. At 1.5 months of age, the patient was treated with intravenous ganciclovir (GCV) for 5 weeks

SUBMITTER: Suganuma E 

PROVIDER: S-EPMC6260854 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature