Mono, bi- and tri-exponential diffusion MRI modelling for renal solid masses and comparison with histopathological findings.

ABSTRACT:

Purpose

To compare diffusion tensor imaging (DTI), intravoxel incoherent motion (IVIM), and tri-exponential models of the diffusion magnetic resonance imaging (MRI) signal for the characterization of renal lesions in relationship to histopathological findings.

Methods

Sixteen patients planned to undergo nephrectomy for kidney tumour were scanned before surgery at 3 T magnetic resonance imaging (MRI), with T₂-weighted imaging, DTI and diffusion weighted imaging (DWI) using ten b-values. DTI parameters (mean diffusivity [MD] and fractional anisotropy [FA]) were obtained by iterative weighted linear least squared fitting of the DTI data and bi-, and tri-exponential fit parameters (D_bi, f_star,and D_tri, f_fast,f_interm

SUBMITTER: van Baalen S 

PROVIDER: S-EPMC6260899 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature