Clinical and Genetic Risk Factors Associated with Psoriatic Arthritis among Patients with Psoriasis.

ABSTRACT:

Introduction

Psoriatic arthritis (PsA) is a chronic, inflammatory arthritis that affects an estimated 30% of patients with psoriasis. PsA is underdiagnosed in primary care and dermatology clinics due to a variety of reasons, including failure of healthcare providers to ask about symptoms, overlap of symptoms and signs with other rheumatologic conditions, and lack of a specific diagnostic test. A delay in PsA diagnosis and treatment, even as short as 6 months, can lead to decreased quality of life, increased joint damage, and worse long-term physical function. In this study, we sought to identify the clinical and genetic factors that help discriminate patients with PsA from those with cutaneous psoriasis only.

Methods

We analyzed a cohort of 974 psoriasis patients at an acade

SUBMITTER: Yan D 

PROVIDER: S-EPMC6261122 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature