Spectral-Domain OCT Findings of Retinal Vascular-Avascular Junction in Infants with Retinopathy of Prematurity.

ABSTRACT:

Purpose

Bedside examination of premature infants at risk for retinopathy of prematurity (ROP) is predominantly performed with ophthalmoscopic en face viewing of the retina. While postmortem retinal microstructures have been studied at the vascular-avascular junction, a critical location for pathogenesis of ROP, to date this has not been possible in vivo. Here we present bedside, non-sedated in vivo cross-sectional imaging and analysis of retinal microstructures at the vascular-avascular junction in infants with ROP using handheld spectral-domain optical coherence tomography (SDOCT).

Design

Prospective observational study.

Participants

Eleven preterm infants consented for research imaging during ROP screening examinations.

Methods

We imaged

SUBMITTER: Chen X 

PROVIDER: S-EPMC6261282 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature