Radiogenomic Predictors of Adverse Effects following Charged Particle Therapy.

ABSTRACT: Radiogenomics is the study of genomic factors that are associated with response to radiation therapy. In recent years, progress has been made toward identifying genetic risk factors linked with late radiation-induced adverse effects. These advances have been underpinned by the establishment of an international Radiogenomics Consortium with collaborative studies that expand cohort sizes to increase statistical power and efforts to improve methodologic approaches for radiogenomic research. Published studies have predominantly reported the results of research involving patients treated with photons using external beam radiation therapy. These studies demonstrate our ability to pool international cohorts to identify common single nucleotide polymorphisms associated with risk for developing nor

SUBMITTER: Morton LM 

PROVIDER: S-EPMC6261418 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature