Serum Beta Carotene and Overall and Cause-Specific Mortality.

ABSTRACT:

Rationale

Although the health effects of beta carotene have been studied extensively, a systematic examination of serum concentrations and long-term mortality, including cardiovascular disease mortality, has not been reported.

Objective

Explore whether serum beta carotene is associated with overall and cause-specific mortality and to elucidate the strength and dose-response of the association.

Methods and results

We conducted a prospective serological analysis of 29 103 men in the ATBC study (Alpha-Tocopherol, Beta-Carotene Cancer Prevention). During 31 years of follow-up, 23 796 deaths occurred, including deaths because of cardiovascular disease (9869), cancer (7692), respiratory disease (2161), diabetes mellitus (119), injuries and accidents (1255), and other causes

SUBMITTER: Huang J 

PROVIDER: S-EPMC6261515 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature